1. V. Brochard, B. Combadiere, A. Prigent, Y. Laouar, A. Perrin, V. Beray-Berthat, O. Bonduelle, D. Alvarez-Fischer, J. Callebert, J. M. Launay, C. Duyckaerts, R. A. Flavell, E. C. Hirsch, and S. Hunot. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest, 119(1):182-92, 2009. Note: Howard Hughes Medical Institute/United StatesJournal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW]



2. S. Guerreiro, A. Ponceau, D. Toulorge, E. Martin, D. Alvarez-Fischer, E. C. Hirsch, and P. P. Michel. Protection of Midbrain Dopaminergic Neurons by the End-Product of Purine Metabolism Uric Acid: Potentiation by Low-Level Depolarization. J Neurochem, 109(4):1118-1128, 2009. Note: Journal article. [WWW]



3. D. Alvarez-Fischer, S. Guerreiro, S. Hunot, F. Saurini, M. Marien, P. Sokoloff, E. C. Hirsch, A. Hartmann, and P. P. Michel. Modelling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid. J Neurochem, 107(3):701-11, 2008. Note: Journal ArticleResearch Support, Non-U.S. Gov'tEngland. [WWW] Keyword(s): 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine/*administration & dosage, Adjuvants, Pharmaceutic/administration & dosage, Animals, Brain/drug effects/pathology, Chromatography, High Pressure Liquid, *Disease Models, Animal, Dopamine/analysis/metabolism, Immunohistochemistry, *Infusion Pumps, Male, Mice, Mice, Inbred C57BL, Nerve Degeneration/chemically induced, Neurotoxins/*administration & dosage, Parkinsonian Disorders/*chemically induced, Probenecid/*administration & dosage.



4. D. Alvarez-Fischer, C. Henze, C. Strenzke, J. Westrich, B. Ferger, G. U. Hoglinger, W. H. Oertel, and A. Hartmann. Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice. Exp Neurol, 210(1):182-93, 2008. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adrenergic Agents/*toxicity, Animals, Behavior, Animal/drug effects, Brain Chemistry/drug effects, Corpus Striatum/*drug effects, Disease Models, Animal, Dose-Response Relationship, Drug, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Motor Activity/drug effects, Oxidopamine/*toxicity, *Parkinson Disease/etiology/genetics/physiopathology, Rotarod Performance Test/methods, Substantia Nigra/metabolism, Time Factors, Tyrosine 3-Monooxygenase/metabolism, alpha-Synuclein/*deficiency.



5. J. Salazar, N. Mena, S. Hunot, A. Prigent, D. Alvarez-Fischer, M. Arredondo, C. Duyckaerts, V. Sazdovitch, L. Zhao, L. M. Garrick, M. T. Nunez, M. D. Garrick, R. Raisman-Vozari, and E. C. Hirsch. Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease. Proc Natl Acad Sci U S A, 105(47):18578-83, 2008. Note: Journal ArticleUnited States. [WWW]



6. D. Alvarez-Fischer, G. Blessmann, C. Trosowski, M. Behe, T. Schurrat, A. Hartmann, T. M. Behr, W. H. Oertel, G. U. Hoglinger, and H. Hoffken. Quantitative [(123)I]FP-CIT pinhole SPECT imaging predicts striatal dopamine levels, but not number of nigral neurons in different mouse models of Parkinson's disease. Neuroimage, 38(1):5-12, 2007. Note: Journal ArticleUnited States. [WWW]



7. G. U. Hoglinger, J. J. Breunig, C. Depboylu, C. Rouaux, P. P. Michel, D. Alvarez-Fischer, A. L. Boutillier, J. Degregori, W. H. Oertel, P. Rakic, E. C. Hirsch, and S. Hunot. The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A, 104(9):3585-90, 2007. Note: R24 mh 68855/mh/nimhComparative StudyJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine/pharmacology, 1-Methyl-4-phenylpyridinium/pharmacology, Analysis of Variance, Animals, Apoptosis/*physiology, Chromatography, High Pressure Liquid, E2F1 Transcription Factor/genetics/*metabolism, Gene Expression Regulation/drug effects, Humans, Immunohistochemistry, In Situ Hybridization, Interneurons/drug effects/*metabolism, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Oligonucleotides, Antisense/genetics, Parkinson Disease/*physiopathology, Signal Transduction/drug effects, Substantia Nigra/*metabolism.



8. P. P. Michel, D. Alvarez-Fischer, S. Guerreiro, A. Hild, A. Hartmann, and E. C. Hirsch. Role of activity-dependent mechanisms in the control of dopaminergic neuron survival. J Neurochem, 101(2):289-97, 2007. Note: Journal ArticleResearch Support, Non-U.S. Gov'tReviewEngland. [WWW] Keyword(s): Action Potentials/*physiology, Animals, Cell Survival/physiology, Dopamine/*metabolism, Humans, Ion Channels/*metabolism, Na(+)-K(+)-Exchanging ATPase/metabolism, Neurons/*metabolism, Parkinson Disease/metabolism/physiopathology, Receptors, Neurotransmitter/metabolism, Substantia Nigra/*metabolism.

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