1. A. P. Bemelmans, I. Husson, M. Jaquet, J. Mallet, B. E. Kosofsky, and P. Gressens. Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge. J Neurosci Res, 83(1):50-60, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, Animals, Newborn/*physiology, Astrocytes/metabolism, Brain-Derived Neurotrophic Factor/*genetics, DNA, Complementary/biosynthesis/genetics, Enzyme-Linked Immunosorbent Assay, Excitatory Amino Acid Agonists/toxicity, Female, *Gene Transfer Techniques, Genetic Vectors, Green Fluorescent Proteins/genetics, HIV-1/genetics, Hela Cells, Humans, Injections, Intraventricular, Lentivirus/*genetics, Male, Mice, N-Methylaspartate/toxicity, *Neuroprotective Agents, Neurotoxins/*antagonists & inhibitors/*toxicity, Rats, Recombinant Proteins/pharmacology.



2. M. Brizard, C. Carcenac, A. P. Bemelmans, C. Feuerstein, J. Mallet, and M. Savasta. Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease. Neurobiol Dis, 21(1):90-101, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, Corpus Striatum/physiopathology, Disease Models, Animal, Dopamine/*physiology, Gene Therapy/*methods, Glial Cell Line-Derived Neurotrophic Factor/*genetics, Lentivirus/genetics, Male, Movement, Nerve Degeneration/physiopathology/therapy, *Nerve Regeneration, Oxidopamine/toxicity, Parkinson Disease/physiopathology/*therapy, Presynaptic Terminals/physiology, Rats, Rats, Sprague-Dawley, Recovery of Function, Sympatholytics/toxicity.



3. B. E. Molles, U. Maskos, S. Pons, M. Besson, P. Guiard, J. P. Guilloux, A. Evrard, A. Cormier, M. Mameli-Engvall, I. Cloez-Tayarani, H. Nakatani, N. Dufour, A. P. Bemelmans, J. Mallet, P. Cazala, A. M. Gardier, V. David, P. Faure, S. Granon, and J. P. Changeux. Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors. J Mol Neurosci, 30(1-2):105-6, 2006. Note: Journal ArticleUnited StatesMn. [WWW] Keyword(s): Animals, Behavior, Addictive/genetics, Brain/*physiology, Cognition/physiology, Exploratory Behavior, *Genetic Vectors, Lentivirus/*genetics, Mice, Mice, Knockout, Nicotine, Receptors, Nicotinic/deficiency/*genetics, Recombinant Proteins/metabolism.



4. A. P. Bemelmans, S. Bonnel, L. Houhou, N. Dufour, E. Nandrot, D. Helmlinger, C. Sarkis, M. Abitbol, and J. Mallet. Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter. J Gene Med, 7(10):1367-74, 2005. Note: Journal ArticleResearch Support, Non-U.S. Gov'tEngland. [WWW] Keyword(s): Animals, Genetic Vectors, Green Fluorescent Proteins/biosynthesis/genetics, HIV-1/*genetics, Injections, Lyssavirus/genetics, Photoreceptors, Vertebrate/metabolism, Pigment Epithelium of Eye/metabolism, *Promoter Regions (Genetics), Rats, Retina/*metabolism, Vesicular stomatitis-Indiana virus/genetics, Viral Envelope Proteins/genetics.



5. C. Girard, A. P. Bemelmans, N. Dufour, J. Mallet, C. Bachelin, B. Nait-Oumesmar, A. Baron-Van Evercooren, and F. Lachapelle. Grafts of brain-derived neurotrophic factor and neurotrophin 3-transduced primate Schwann cells lead to functional recovery of the demyelinated mouse spinal cord. J Neurosci, 25(35):7924-33, 2005. Note: Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official journal of the Society for Neuroscience. [WWW] Keyword(s): Animals, Brain-Derived Neurotrophic Factor/genetics/*secretion, Cell Transplantation/methods, Cells, Cultured, Demyelinating Diseases/genetics/*metabolism/pathology/surgery, Female, Humans, Macaca fascicularis, Male, Mice, Mice, Nude, Nerve Fibers, Myelinated/metabolism/pathology/secretion, Neurotrophin 3/genetics/*secretion, Recovery of Function/*physiology, Schwann Cells/metabolism/*transplantation, Spinal Cord/*metabolism/pathology/transplantation, Transduction, Genetic/methods, Transplants.



6. I. Husson, C. M. Rangon, V. Lelievre, A. P. Bemelmans, P. Sachs, J. Mallet, B. E. Kosofsky, and P. Gressens. BDNF-induced white matter neuroprotection and stage-dependent neuronal survival following a neonatal excitotoxic challenge. Cereb Cortex, 15(3):250-61, 2005. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States1991). [WWW] Keyword(s): Animals, Animals, Newborn, Astrocytes/drug effects/*metabolism/*pathology, Brain-Derived Neurotrophic Factor/*pharmacology, Cell Survival/drug effects, Cerebral Cortex/drug effects/metabolism/pathology, Cerebral Palsy/chemically induced/*metabolism/*pathology, Female, Male, Mice, Neurons/drug effects/*metabolism/*pathology, Neuroprotective Agents/pharmacology, Neurotoxins.



7. U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J. P. Guilloux, A. Evrard, P. Cazala, A. Cormier, M. Mameli-Engvall, N. Dufour, I. Cloez-Tayarani, A. P. Bemelmans, J. Mallet, A. M. Gardier, V. David, P. Faure, S. Granon, and J. P. Changeux. Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors. Nature, 436(7047):103-7, 2005. Note: Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.England. [WWW] Keyword(s): Animals, Cognition/drug effects/*physiology, Dopamine/metabolism, Exploratory Behavior/drug effects/physiology, *Gene Expression, Locomotion/physiology, Mice, Morphine/administration & dosage/pharmacology, Neurons/drug effects/metabolism, Nicotine/administration & dosage/*metabolism/pharmacology, Receptors, Adrenergic, beta-2/deficiency/genetics/metabolism, Receptors, Nicotinic/deficiency/genetics/*metabolism, Ventral Tegmental Area/cytology/drug effects/physiology.

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