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3. D. J. Brooks, Y. Agid, K. Eggert, H. Widner, K. Ostergaard, and A. Holopainen. Treatment of end-of-dose wearing-off in parkinson's disease: stalevo (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess/Comtan (entacapone) provide equivalent improvements in symptom control superior to that of traditional levodopa/DDCI treatment. Eur Neurol, 53(4):197-202, 2005. Note: TC-INIT Study GroupClinical TrialComparative StudyJournal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov'tSwitzerland. [WWW] Keyword(s): Aged, Antiparkinson Agents/*therapeutic use, Carbidopa/*therapeutic use, Catechols/*therapeutic use, Disability Evaluation, Drug Combinations, Drug Evaluation/methods, Drug Therapy, Combination, Enzyme Inhibitors/*therapeutic use, Female, Follow-Up Studies, Humans, Levodopa/*therapeutic use, Male, Middle Aged, Motor Activity/drug effects, Pain Measurement, Parkinson Disease/*drug therapy, Quality of Life, Questionnaires, Severity of Illness Index, Single-Blind Method, Treatment Outcome.

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