1. A. Rachalski, C. Alexandre, J. F. Bernard, F. Saurini, K. P. Lesch, M. Hamon, J. Adrien, and V. Fabre. Altered sleep homeostasis after restraint stress in 5-HTT knock-out male mice: a role for hypocretins. J Neurosci, 29(49):15575-85, 2009. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official journal of the Society for Neuroscience. [WWW]



2. I. Sahly, V. Fabre, S. Vyas, A. Milet, J. D. Rouzeau, M. Hamon, M. Lazar, and F. Tronche. 5-HT1A-iCre, a new transgenic mouse line for genetic analyses of the serotonergic pathway. Mol Cell Neurosci, 36(1):27-35, 2007. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, Behavior, Animal/physiology, Brain/embryology/growth & development/*metabolism, Embryo, Mammalian, Gene Expression Regulation, Developmental/genetics, Integrases/genetics/*metabolism, Mice, Mice, Inbred C57BL, Mice, Transgenic/*genetics, Receptor, Serotonin, 5-HT1A/*genetics, Serotonin/genetics/*metabolism, Signal Transduction/*genetics.



3. C. Alexandre, D. Popa, V. Fabre, S. Bouali, P. Venault, K. P. Lesch, M. Hamon, and J. Adrien. Early life blockade of 5-hydroxytryptamine 1A receptors normalizes sleep and depression-like behavior in adult knock-out mice lacking the serotonin transporter. J Neurosci, 26(20):5554-64, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official journal of the Society for Neuroscience. [WWW] Keyword(s): Animals, Binding Sites/drug effects/genetics, Binding, Competitive/drug effects/genetics, Brain/*drug effects/growth & development/physiopathology, Brain Chemistry/drug effects/genetics, Depressive Disorder/*drug therapy/genetics/physiopathology, Disease Models, Animal, Female, Male, Mice, Mice, Knockout, Mutation/genetics, Neural Pathways/drug effects/growth & development/physiopathology, RNA, Messenger/drug effects/metabolism, Raphe Nuclei/drug effects/growth & development/physiopathology, Receptor, Serotonin, 5-HT1A/*antagonists & inhibitors/genetics/metabolism, Serotonin/*metabolism, Serotonin Antagonists/pharmacology, Serotonin Plasma Membrane Transport Proteins/*genetics, Sleep Disorders/*drug therapy/genetics/physiopathology, Sleep, REM/drug effects/genetics.



4. B. Conti, M. Sanchez-Alavez, R. Winsky-Sommerer, M. C. Morale, J. Lucero, S. Brownell, V. Fabre, S. Huitron-Resendiz, S. Henriksen, E. P. Zorrilla, L. de Lecea, and T. Bartfai. Transgenic mice with a reduced core body temperature have an increased life span. Science, 314(5800):825-8, 2006. Note: Mh58543/mh/nimhNs043501/ns/nindsJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Aging, Animals, *Body Temperature, Body Temperature Regulation, Body Weight, Circadian Rhythm, Drinking, Eating, Energy Metabolism, Female, Hypothalamic Area, Lateral/cytology/metabolism, Intracellular Signaling Peptides and Proteins/metabolism, Ion Channels/genetics/physiology, *Longevity, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Mitochondrial Proteins/genetics/physiology, Neurons/metabolism, Neuropeptides/metabolism, Preoptic Area/cytology/*physiology, Thermogenesis.



5. D. Popa, C. Lena, V. Fabre, C. Prenat, J. Gingrich, P. Escourrou, M. Hamon, and J. Adrien. Contribution of 5-HT2 receptor subtypes to sleep-wakefulness and respiratory control, and functional adaptations in knock-out mice lacking 5-HT2A receptors. J Neurosci, 25(49):11231-8, 2005. Note: Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official journal of the Society for Neuroscience. [WWW] Keyword(s): Adaptation, Physiological/genetics/*physiology, Animals, Male, Mice, Mice, Knockout, Pulmonary Ventilation/genetics/*physiology, Receptor, Serotonin, 5-HT2A/agonists/antagonists &, inhibitors/deficiency/physiology, Receptors, Serotonin, 5-HT2/agonists/antagonists &, inhibitors/deficiency/*genetics, Serotonin Agonists/pharmacology, Serotonin Antagonists/pharmacology, Sleep/drug effects/genetics/*physiology, Sleep Deprivation/genetics/metabolism, Wakefulness/drug effects/genetics/*physiology.



6. A. D. Spier, V. Fabre, and L. de Lecea. Cortistatin radioligand binding in wild-type and somatostatin receptor-deficient mouse brain. Regul Pept, 124(1-3):179-86, 2005. Note: Mh58543/mh/nimhJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Netherlands. [WWW] Keyword(s): Animals, Autoradiography, Binding, Competitive, Brain/cytology/*metabolism, Iodine Radioisotopes, Ligands, Mice, Mice, Knockout, Neuropeptides/*metabolism, Peptides, Cyclic/*metabolism, Radioligand Assay, Receptors, Somatostatin/*deficiency/genetics/*metabolism, Somatostatin/metabolism, Tyrosine/metabolism.



7. M. K. Tallent, V. Fabre, C. Qiu, M. Calbet, T. Lamp, M. V. Baratta, C. Suzuki, C. L. Levy, G. R. Siggins, S. J. Henriksen, J. R. Criado, A. Roberts, and L. de Lecea. Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning. Mol Cell Neurosci, 30(3):465-75, 2005. Note: Da08301/da/nidaMh44346/mh/nimhMh58543/mh/nimhNs38633/ns/nindsJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, P.H.S.United States. [WWW] Keyword(s): Aging/genetics/metabolism, Animals, Dentate Gyrus/metabolism/physiopathology, Female, Gene Expression Regulation, Developmental/genetics, Hippocampus/*metabolism, Learning/*physiology, Learning Disorders/*genetics/metabolism/physiopathology, Long-Term Potentiation/*genetics, Male, Memory Disorders/genetics/metabolism/physiopathology, Mice, Mice, Transgenic, Peptides/genetics/*metabolism, Promoter Regions (Genetics)/genetics, Synaptic Transmission/*genetics.



8. R. Winsky-Sommerer, A. D. Spier, V. Fabre, L. de Lecea, and J. R. Criado. Overexpression of the human beta-amyloid precursor protein downregulates cortistatin mRNA in PDAPP mice. Brain Res, 1023(1):157-62, 2004. Note: Da12669/da/nidaMh58543/mh/nimhComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Netherlands. [WWW] Keyword(s): Aging/genetics, Amyloid beta-Protein Precursor/*biosynthesis/*genetics/physiology, Animals, Down-Regulation/*genetics, Female, Gene Expression Regulation/physiology, Humans, Mice, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, Transgenic, Neuropeptides/*antagonists & inhibitors/biosynthesis, Protein Precursors/metabolism, RNA, Messenger/*metabolism, Receptor, Platelet-Derived Growth Factor beta/biosynthesis/genetics.

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