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Publications of S. Lesage
Articles in journal or book chapters
  1. E. Evangelou, D. M. Maraganore, G. Annesi, L. Brighina, A. Brice, A. Elbaz, C. Ferrarese, G. M. Hadjigeorgiou, R. Krueger, J. C. Lambert, S. Lesage, K. Markopoulou, G. D. Mellick, B. Meeus, N. L. Pedersen, A. Quattrone, C. Van Broeckhoven, M. Sharma, P. A. Silburn, E. K. Tan, K. Wirdefeldt, and J. P. Ioannidis. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: Large-scale collaborative study. Am J Med Genet B Neuropsychiatr Genet, 153B(1):220-228, 2010. [WWW]


  2. S. Lesage, E. Patin, C. Condroyer, A. L. Leutenegger, E. Lohmann, N. Giladi, A. Bar-Shira, S. Belarbi, N. Hecham, P. Pollak, A. M. Ouvrard-Hernandez, S. Bardien, J. Carr, T. Benhassine, H. Tomiyama, C. Pirkevi, T. Hamadouche, C. Cazeneuve, A. N. Basak, N. Hattori, A. Durr, M. Tazir, A. Orr-Urtreger, L. Quintana-Murci, and A. Brice. Parkinson's disease-related LRRK2 G2019S mutation results from independent mutational events in humans. Hum Mol Genet, 2010. Note: For the French Parkinson's Disease Genetics Study GroupJournal article. [WWW]


  3. P. Ibanez, S. Lesage, S. Janin, E. Lohmann, F. Durif, A. Destee, A. M. Bonnet, C. Brefel-Courbon, S. Heath, D. Zelenika, Y. Agid, A. Durr, and A. Brice. Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms. Arch Neurol, 66(1):102-8, 2009. Note: French Parkinson's Disease Genetics Study GroupJournal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adult, Aged, Aged, 80 and over, Brain Chemistry/*genetics, Chromosome Breakage, DNA Mutational Analysis, DNA Repeat Expansion/genetics, Female, Gene Dosage/genetics, Genes, Dominant/*genetics, Genetic Predisposition to Disease/*genetics, Genetic Screening, Genotype, Haplotypes/genetics, Humans, Male, Microsatellite Repeats/genetics, Middle Aged, Oligonucleotide Array Sequence Analysis, Parkinsonian Disorders/*genetics/*metabolism/physiopathology, Polymorphism, Single Nucleotide/genetics, alpha-Synuclein/*genetics.


  4. S. Lesage, C. Condroyer, A. Lannuzel, E. Lohmann, A. Troiano, F. Tison, P. Damier, S. Thobois, A. M. Ouvrard-Hernandez, S. Rivaud-Pechoux, C. Brefel-Courbon, A. Destee, C. Tranchant, M. Romana, L. Leclere, A. Durr, and A. Brice. Molecular analyses of the LRRK2 gene in European and North African autosomal dominant Parkinson's disease. J Med Genet, 46(7):458-64, 2009. Note: French Parkinson's Disease Genetics Study GroupLetterResearch Support, Non-U.S. Gov'tEngland. [WWW] Keyword(s): Adolescent, Adult, African Continental Ancestry Group/genetics, Aged, Aged, 80 and over, Analysis of Variance, Chi-Square Distribution, DNA Mutational Analysis/methods, European Continental Ancestry Group/genetics, Female, Gene Frequency, Humans, Male, Middle Aged, Mutation, Parkinsonian Disorders/diagnosis/*genetics, Pedigree, Protein-Serine-Threonine Kinases/*genetics.


  5. E. Lohmann, L. Leclere, F. De Anna, S. Lesage, B. Dubois, Y. Agid, A. Durr, and A. Brice. A clinical, neuropsychological and olfactory evaluation of a large family with LRRK2 mutations. Parkinsonism Relat Disord, 15(4):273-6, 2009. Note: French Parkinson's Disease Genetics Study GroupJournal ArticleResearch Support, Non-U.S. Gov'tEngland. [WWW] Keyword(s): Aged, DNA Mutational Analysis/methods, *Family Health, Female, France, *Genetic Predisposition to Disease, Glycine/genetics, Humans, Male, Middle Aged, Mutation/*genetics, Neuropsychological Tests, *Olfaction Disorders/etiology/genetics/psychology, *Parkinson Disease/complications/genetics/psychology, Protein-Serine-Threonine Kinases/*genetics, Serine/genetics.


  6. E. Lohmann, S. Thobois, S. Lesage, E. Broussolle, S. T. du Montcel, M. J. Ribeiro, P. Remy, A. Pelissolo, B. Dubois, L. Mallet, P. Pollak, Y. Agid, and A. Brice. A multidisciplinary study of patients with early-onset PD with and without parkin mutations. Neurology, 72(2):110-6, 2009. Note: French Parkinson's Disease Genetics Study GroupNS41723-01A1/NS/NINDS NIH HHS/United StatesJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adult, Age of Onset, Aged, Antiparkinson Agents/administration & dosage/adverse effects, Cognition Disorders/diagnosis/epidemiology/*genetics, Comorbidity, DNA Mutational Analysis, Depressive Disorder/diagnosis/epidemiology/*genetics, Disease Progression, Drug Resistance/genetics, Female, Genetic Predisposition to Disease/*genetics, Genetic Screening, Genotype, Humans, Male, Middle Aged, Parkinson Disease/epidemiology/*genetics/psychology, Severity of Illness Index, Ubiquitin-Protein Ligases/*genetics.


  7. C. Pirkevi, S. Lesage, C. Condroyer, H. Tomiyama, N. Hattori, S. Ertan, A. Brice, and A. N. Basak. A LRRK2 G2019S mutation carrier from Turkey shares the Japanese haplotype. Neurogenetics, 10(3):271-3, 2009. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Aged, Aged, 80 and over, Asian Continental Ancestry Group/*genetics, DNA Mutational Analysis, Female, Genetics, Population, Haplotypes, *Heterozygote, Humans, Japan, Middle Aged, Molecular Sequence Data, Parkinson Disease/genetics, *Point Mutation, Protein-Serine-Threonine Kinases/*genetics, Turkey.


  8. M. J. Ribeiro, S. Thobois, E. Lohmann, S. T. du Montcel, S. Lesage, A. Pelissolo, B. Dubois, L. Mallet, P. Pollak, Y. Agid, E. Broussolle, A. Brice, and P. Remy. A Multitracer Dopaminergic PET Study of Young-Onset Parkinsonian Patients With and Without Parkin Gene Mutations. J Nucl Med, 2009. Note: The French Parkinson's Disease Genetics Study GroupJournal articleofficial publication, Society of Nuclear Medicine. [WWW]


  9. E. Sidransky, M. A. Nalls, J. O. Aasly, J. Aharon-Peretz, G. Annesi, E. R. Barbosa, A. Bar-Shira, D. Berg, J. Bras, A. Brice, C. M. Chen, L. N. Clark, C. Condroyer, E. V. De Marco, A. Durr, M. J. Eblan, S. Fahn, M. J. Farrer, H. C. Fung, Z. Gan-Or, T. Gasser, R. Gershoni-Baruch, N. Giladi, A. Griffith, T. Gurevich, C. Januario, P. Kropp, A. E. Lang, G. J. Lee-Chen, S. Lesage, K. Marder, I. F. Mata, A. Mirelman, J. Mitsui, I. Mizuta, G. Nicoletti, C. Oliveira, R. Ottman, A. Orr-Urtreger, L. V. Pereira, A. Quattrone, E. Rogaeva, A. Rolfs, H. Rosenbaum, R. Rozenberg, A. Samii, T. Samaddar, C. Schulte, M. Sharma, A. Singleton, M. Spitz, E. K. Tan, N. Tayebi, T. Toda, A. R. Troiano, S. Tsuji, M. Wittstock, T. G. Wolfsberg, Y. R. Wu, C. P. Zabetian, Y. Zhao, and S. G. Ziegler. Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. N Engl J Med, 361(17):1651-61, 2009. Note: NS050487/NS/NINDS NIH HHS/United StatesNS060113/NS/NINDS NIH HHS/United StatesNS40256/NS/NINDS NIH HHS/United StatesComparative StudyJournal ArticleMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., IntramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.United States. [WWW] Keyword(s): Aged, Case-Control Studies, Genotype, Glucosylceramidase/*genetics, Humans, Jews/genetics, Logistic Models, Middle Aged, Multivariate Analysis, *Mutation, Odds Ratio, Parkinson Disease/*genetics.


  10. S. Lesage, E. Lohmann, F. Tison, F. Durif, A. Durr, and A. Brice. Gene symbol: PARK2. Disease: Parkinsonism, juvenile, autosomal recessive. Hum Genet, 123(1):114, 2008. Note: Journal ArticleGermany. [WWW] Keyword(s): Amino Acid Substitution, Codon, *Genes, Recessive, Humans, Molecular Sequence Data, Parkinsonian Disorders/*genetics, Ubiquitin-Protein Ligases/chemistry/*genetics.


  11. S. Lesage, E. Lohmann, F. Tison, F. Durif, A. Durr, and A. Brice. Rare heterozygous parkin variants in French early-onset Parkinson disease patients and controls. J Med Genet, 45(1):43-6, 2008. Note: French Parkinson's Disease Genetics Study GroupNS41723-01A1/NS/NINDS NIH HHS/United StatesLetterResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tEngland. [WWW] Keyword(s): Adolescent, Adult, Age of Onset, Aged, Alleles, Case-Control Studies, DNA Mutational Analysis, European Continental Ancestry Group, Exons/genetics, Female, France, Gene Frequency, Genetic Predisposition to Disease, *Genetic Variation, *Heterozygote, Humans, Male, Middle Aged, Parkinson Disease/*genetics/physiopathology, Point Mutation, Ubiquitin-Protein Ligases/*genetics.


  12. E. Lohmann, L. Leclere, F. De Anna, S. Lesage, B. Dubois, Y. Agid, A. Durr, and A. Brice. A clinical, neuropsychological and olfactory evaluation of a large family with LRRK2 mutations. Parkinsonism Relat Disord, 2008. Note: The French Parkinson's Disease Genetics Study GroupJournal article. [WWW]


  13. E. Lohmann, M. L. Welter, V. Fraix, P. Krack, S. Lesage, S. Laine, M. L. Tanguy, J. L. Houeto, V. Mesnage, P. Pollak, A. Durr, Y. Agid, and A. Brice. Are parkin patients particularly suited for deep-brain stimulation?. Mov Disord, 23(5):740-3, 2008. Note: French Parkinson's Disease Genetics study groupNS41723-01A1/NS/United States NINDSJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited Statesofficial journal of the Movement Disorder Society. [WWW] Keyword(s): Adult, Aged, Antiparkinson Agents/adverse effects/therapeutic use, DNA Mutational Analysis, *Deep Brain Stimulation, Dyskinesia, Drug-Induced, Female, Follow-Up Studies, Genetic Screening, Heterozygote, Homozygote, Humans, Levodopa/adverse effects/therapeutic use, Male, Middle Aged, Mutation, Parkinsonian Disorders/*genetics/*therapy, Treatment Outcome, Ubiquitin-Protein Ligases/*genetics.


  14. F. Milhavet, L. Cuisset, H. M. Hoffman, R. Slim, H. El-Shanti, I. Aksentijevich, S. Lesage, H. Waterham, C. Wise, C. Sarrauste de Menthiere, and I. Touitou. The infevers autoinflammatory mutation online registry: update with new genes and functions. Hum Mutat, 29(6):803-8, 2008. Note: Journal ArticleUnited States. [WWW] Keyword(s): Confidentiality, *Databases, Genetic, Familial Mediterranean Fever/*genetics, Humans, Internet, Mutation, *Registries, User-Computer Interface.


  15. P. Charles, A. Camuzat, N. Benammar, F. Sellal, A. Destee, A. M. Bonnet, S. Lesage, I. Le Ber, G. Stevanin, A. Durr, and A. Brice. Are interrupted SCA2 CAG repeat expansions responsible for parkinsonism?. Neurology, 2007. Note: French Parkinson's Disease Genetics Study Group*Journal article. [WWW]


  16. L. N. Clark, E. Haamer, H. Mejia-Santana, J. Harris, S. Lesage, A. Durr, S. J. Bs, K. Hedrich, E. D. Louis, L. J. Cote, H. Andrews, S. Fahn, C. Waters, B. Ford, S. Frucht, W. Scott, C. Klein, A. Brice, H. Roomere, R. Ottman, and K. Marder. Construction and validation of a Parkinson's disease mutation genotyping array for the Parkin gene. Mov Disord, 22(7):932-7, 2007. Note: Ns32527/ns/nindsNs36630/ns/nindsNs41723-01a1/ns/nindsRr00645/rr/ncrrJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited Statesofficial journal of the Movement Disorder Society. [WWW] Keyword(s): Family Health, Gene Expression Profiling/*methods, Genetics, Population, Genotype, Humans, *Mutation, Oligonucleotide Array Sequence Analysis/*methods, Parkinson Disease/epidemiology/*genetics, Reproducibility of Results, Retrospective Studies, Ubiquitin-Protein Ligases/*genetics.


  17. A. Grunewald, G. J. Breedveld, K. Lohmann-Hedrich, C. F. Rohe, I. R. Konig, J. Hagenah, N. Vanacore, G. Meco, A. Antonini, S. Goldwurm, S. Lesage, A. Durr, F. Binkofski, H. Siebner, A. Munchau, A. Brice, B. A. Oostra, C. Klein, and V. Bonifati. Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis. Neurogenetics, 8(2):103-9, 2007. Note: Journal ArticleUnited States. [WWW]


  18. S. Lesage, A. Durr, and A. Brice. LRRK2: a link between familial and sporadic Parkinson's disease?. Pathol Biol (Paris), 55(2):107-10, 2007. Note: EditorialResearch Support, Non-U.S. Gov'tFrance. [WWW] Keyword(s): Adult, Age of Onset, Aged, Aged, 80 and over, Amino Acid Substitution, Animals, Ethnic Groups/genetics, Female, Gene Frequency, Genes, Dominant, Humans, Male, Mice, Middle Aged, Mutation, Missense, Parkinson Disease/epidemiology/*genetics, Phenotype, Point Mutation, Protein Structure, Tertiary, Protein-Serine-Threonine Kinases/chemistry/genetics/*physiology.


  19. S. Lesage, S. Janin, E. Lohmann, A. L. Leutenegger, L. Leclere, F. Viallet, P. Pollak, F. Durif, S. Thobois, V. Layet, M. Vidailhet, Y. Agid, A. Durr, A. Brice, A. M. Bonnet, M. Borg, E. Broussolle, P. Damier, A. Destee, M. Martinez, C. Penet, O. Rasco, F. Tison, C. Tranchan, and M. Verin. LRRK2 exon 41 mutations in sporadic Parkinson disease in Europeans. Arch Neurol, 64(3):425-30, 2007. Note: French Parkinson's Disease Genetics Study GroupNs41723-01a1/ns/nindsComparative StudyJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adolescent, Adult, Aged, Aged, 80 and over, DNA Mutational Analysis/methods, Europe, Exons/*genetics, Female, Histidine/genetics, Humans, Male, Middle Aged, *Mutation, Parkinson Disease/*genetics, Protein-Serine-Threonine Kinases/*genetics, Serine/genetics, Threonine/genetics, Tyrosine/genetics.


  20. S. Lesage, L. Leclere, E. Lohmann, M. Borg, M. Ruberg, A. Durr, and A. Brice. Frequency of the LRRK2 G2019S mutation in siblings with Parkinson's disease. Neurodegener Dis, 4(2-3):195-8, 2007. Note: French Parkinson's Disease Genetics Study GroupNs41723-01a1/ns/nindsJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tSwitzerland. [WWW]


  21. S. Lesage, P. Magali, E. Lohmann, L. Lacomblez, H. Teive, S. Janin, P. Y. Cousin, A. Durr, and A. Brice. Deletion of the parkin and PACRG gene promoter in early-onset parkinsonism. Hum Mutat, 28(1):27-32, 2007. Note: French Parkinson Disease Genetics Study GroupNs41723-01a1/ns/nindsJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tUnited States. [WWW]


  22. M. Schupbach, E. Lohmann, M. Anheim, S. Lesage, V. Czernecki, S. Yaici, Y. Worbe, P. Charles, M. L. Welter, P. Pollak, A. Durr, Y. Agid, and A. Brice. Subthalamic nucleus stimulation is efficacious in patients with Parkinsonism and LRRK2 mutations. Mov Disord, 22(1):119-22, 2007. Note: Clinical TrialComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited Statesofficial journal of the Movement Disorder Society. [WWW] Keyword(s): Adult, Aged, Deep Brain Stimulation/*methods, Female, Glycine/genetics, Humans, Male, Middle Aged, *Mutation, *Parkinsonian Disorders/genetics/pathology/therapy, Protein-Serine-Threonine Kinases/*genetics, Retrospective Studies, Serine/genetics, Subthalamic Nucleus/physiology/*surgery, Threonine/genetics.


  23. P. Ibanez, S. Lesage, E. Lohmann, S. Thobois, G. De Michele, M. Borg, Y. Agid, A. Durr, and A. Brice. Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa. Brain, 129(Pt 3):686-94, 2006. Note: French Parkinson's Disease Genetics Study GroupNs41723-01a1/ns/nindsCase ReportsJournal ArticleMulticenter StudyResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tEnglanda journal of neurology. [WWW] Keyword(s): Adult, Age of Onset, Aged, Amino Acid Sequence, DNA Mutational Analysis, Female, Humans, Male, Middle Aged, Molecular Sequence Data, *Mutation, Parkinsonian Disorders/*genetics, Pedigree, Protein Kinases/*genetics, Sequence Alignment, Ubiquitin-Protein Ligases/genetics.


  24. L. Ishihara, L. Warren, R. Gibson, R. Amouri, S. Lesage, A. Durr, M. Tazir, Z. K. Wszolek, R. J. Uitti, W. C. Nichols, A. Griffith, N. Hattori, D. Leppert, R. Watts, C. P. Zabetian, T. M. Foroud, M. J. Farrer, A. Brice, L. Middleton, and F. Hentati. Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations. Arch Neurol, 63(9):1250-4, 2006. Note: K08 ns 044138/ns/nindsNs 41723-01a1/ns/nindsP50 ns 40256-02/ns/nindsR01 ns 037167/ns/nindsComparative StudyJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.United States. [WWW] Keyword(s): Aged, DNA Mutational Analysis/methods, *Family Health, Female, Gene Frequency, Genetic Predisposition to Disease, Glycine/*genetics, Humans, Male, Middle Aged, *Mutation, Parkinson Disease/epidemiology/*genetics, Protein-Serine-Threonine Kinases/*genetics, Serine/*genetics.


  25. S. Lesage, A. Durr, and A. Brice. [LRRK2 is a major gene in North African parkinsonism]. Med Sci (Paris), 22(5):470-1, 2006. Note: NewsFranceM/s. [WWW] Keyword(s): Africa, Northern, Humans, Parkinsonian Disorders/*genetics, Protein-Serine-Threonine Kinases/*genetics.


  26. S. Lesage, A. Durr, M. Tazir, E. Lohmann, A. L. Leutenegger, S. Janin, P. Pollak, and A. Brice. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med, 354(4):422-3, 2006. Note: French Parkinson's Disease Genetics Study GroupLetterUnited States. [WWW] Keyword(s): Africa, Northern/ethnology, Arabs/*genetics, Heterozygote, Homozygote, Humans, Middle Aged, Mutation, Parkinson Disease/*genetics, Protein-Serine-Threonine Kinases/*genetics.


  27. A. L. Leutenegger, M. A. Salih, P. Ibanez, M. M. Mukhtar, S. Lesage, A. Arabi, E. Lohmann, A. Durr, A. E. Ahmed, and A. Brice. Juvenile-onset Parkinsonism as a result of the first mutation in the adenosine triphosphate orientation domain of PINK1. Arch Neurol, 63(9):1257-61, 2006. Note: Ns 41723-01a1/ns/nindsComparative StudyJournal ArticleResearch Support, N.I.H., ExtramuralUnited States. [WWW] Keyword(s): Adenosine Triphosphate/*metabolism, Adolescent, Adult, Age of Onset, Alanine/genetics, Amino Acid Sequence, Aspartic Acid/genetics, DNA Mutational Analysis, *Family Health, Female, Genetic Predisposition to Disease, Humans, Male, Middle Aged, *Mutation, Parkinsonian Disorders/*genetics, Protein Kinases/*genetics, Sudan.


  28. N. Pineda-Trujillo, M. Apergi, S. Moreno, W. Arias, S. Lesage, A. Franco, D. Sepulveda-Falla, D. Cano, O. Buritica, D. Pineda, C. S. Uribe, J. G. de Yebenes, A. J. Lees, A. Brice, G. Bedoya, F. Lopera, and A. Ruiz-Linares. A genetic cluster of early onset Parkinson's disease in a Colombian population. Am J Med Genet B Neuropsychiatr Genet, 141(8):885-9, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official publication of the International Society of Psychiatric Genetics. [WWW]


  29. S. Lesage, P. Ibanez, E. Lohmann, P. Pollak, F. Tison, M. Tazir, A. L. Leutenegger, J. Guimaraes, A. M. Bonnet, Y. Agid, A. Durr, and A. Brice. G2019S LRRK2 mutation in French and North African families with Parkinson's disease. Ann Neurol, 58(5):784-7, 2005. Note: French Parkinson's Disease Genetics Study GroupComparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adult, Africa, Northern/epidemiology/ethnology, Aged, Aged, 80 and over, DNA Mutational Analysis/methods, *Family Health, Female, France/epidemiology/ethnology, Gene Frequency, Genetic Predisposition to Disease, Genotype, Glycine/*genetics, Humans, Male, Mental Status Schedule/statistics & numerical data, Middle Aged, *Mutation, Parkinson Disease/*genetics, Protein-Serine-Threonine Kinases/*genetics, Serine/*genetics.


  30. S. Lesage, A. L. Leutenegger, and A. Brice. [LRRK2: a gene belonging to the ROCO family is implicated in the Parkinson's disease]. Med Sci (Paris), 21(12):1015-7, 2005. Note: NewsFranceM/s. [WWW] Keyword(s): Humans, Parkinson Disease/*genetics, Protein-Serine-Threonine Kinases/*genetics.


  31. S. Lesage, A. L. Leutenegger, P. Ibanez, S. Janin, E. Lohmann, A. Durr, and A. Brice. LRRK2 haplotype analyses in European and North African families with Parkinson disease: a common founder for the G2019S mutation dating from the 13th century. Am J Hum Genet, 77(2):330-2, 2005. Note: French Parkinson's Disease Genetics Study GroupLetterResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Africa, Northern, African Continental Ancestry Group, European Continental Ancestry Group, Family Health, *Founder Effect, Genetic Markers, Genotype, *Haplotypes, Humans, Microsatellite Repeats, Middle Aged, *Mutation, Parkinson Disease/*genetics, Protein-Serine-Threonine Kinases/*genetics.



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