1. S. Guerreiro, A. Ponceau, D. Toulorge, E. Martin, D. Alvarez-Fischer, E. C. Hirsch, and P. P. Michel. Protection of Midbrain Dopaminergic Neurons by the End-Product of Purine Metabolism Uric Acid: Potentiation by Low-Level Depolarization. J Neurochem, 109(4):1118-1128, 2009. Note: Journal article. [WWW]



2. S. Hanein, E. Martin, A. Boukhris, P. Byrne, C. Goizet, A. Hamri, A. Benomar, A. Lossos, P. Denora, J. Fernandez, N. Elleuch, S. Forlani, A. Durr, I. Feki, M. Hutchinson, F. M. Santorelli, C. Mhiri, A. Brice, and G. Stevanin. Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome. Am J Hum Genet, 82(4):992-1002, 2008. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW]



3. Morwena Latouche, Christelle Lasbleiz, Elodie Martin, Veronique Monnier, Thomas Debeir, Annick Mouatt-Prigent, Marie-Paule Muriel, Lydie Morel, Merle Ruberg, Alexis Brice, Giovanni Stevanin, and Herve Tricoire. A Conditional Pan-Neuronal Drosophila Model of Spinocerebellar Ataxia 7 with a Reversible Adult Phenotype Suitable for Identifying Modifier Genes. J Neurosci, 27(10):2483-2492, 2007. [WWW] [doi:10.1523/jneurosci.5453-06.2007]



4. M. Latouche, C. Lasbleiz, E. Martin, V. Monnier, T. Debeir, A. Mouatt-Prigent, M. P. Muriel, L. Morel, M. Ruberg, A. Brice, G. Stevanin, and H. Tricoire. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes. J Neurosci, 27(10):2483-92, 2007. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited Statesthe official journal of the Society for Neuroscience. [WWW] Keyword(s): Animals, Animals, Genetically Modified, Cell Death, Cells, Cultured, *Disease Models, Animal, *Drosophila, Dyskinesias/genetics, Glutamine, Humans, Intranuclear Inclusion Bodies/ultrastructure, Longevity, Male, Mutation, Nerve Tissue Proteins/genetics/metabolism, Neurons/metabolism, Peptides/genetics, Phenotype, Rats, Spinocerebellar Ataxias/*genetics/metabolism/pathology/physiopathology, Threonine.



5. M. Namekawa, M. P. Muriel, A. Janer, M. Latouche, A. Dauphin, T. Debeir, E. Martin, C. Duyckaerts, A. Prigent, C. Depienne, A. Sittler, A. Brice, and M. Ruberg. Mutations in the SPG3A gene encoding the GTPase atlastin interfere with vesicle trafficking in the ER/Golgi interface and Golgi morphogenesis. Mol Cell Neurosci, 35(1):1-13, 2007. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Adult, Cell Line, Cytoplasmic Vesicles/*enzymology/ultrastructure, Endoplasmic Reticulum/*enzymology/ultrastructure, Epitopes, GTP Phosphohydrolases/*genetics/*metabolism, Golgi Apparatus/*enzymology/ultrastructure, Humans, Kidney/cytology, Microscopy, Electron, Motor Cortex/cytology, Motor Neurons/*enzymology, Paraplegia/genetics/metabolism, Point Mutation, Protein Transport/physiology, Spinal Cord/cytology.



6. G. Stevanin, F. M. Santorelli, H. Azzedine, P. Coutinho, J. Chomilier, P. S. Denora, E. Martin, A. M. Ouvrard-Hernandez, A. Tessa, N. Bouslam, A. Lossos, P. Charles, J. L. Loureiro, N. Elleuch, C. Confavreux, V. T. Cruz, M. Ruberg, E. Leguern, D. Grid, M. Tazir, B. Fontaine, A. Filla, E. Bertini, A. Durr, and A. Brice. Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. Nat Genet, 39(3):366-372, 2007. Note: Journal article. [WWW]



7. G. Stevanin, F. Santorelli, H. Azzedine, P. Coutinho, P. Denora, E. Martin, A. Lossos, B. Fontaine, A. Filla, E. Bertini, A. Durr, and A. Brice. Mutations in the SPG11 gene are a major cause of spastic paraplegia with thin corpus callosum. Neurology, 68(12):A201-A201, 2007. Note: Suppl. 1. [WWW]



8. A. Janer, E. Martin, M. P. Muriel, M. Latouche, H. Fujigasaki, M. Ruberg, A. Brice, Y. Trottier, and A. Sittler. PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins. J Cell Biol, 174(1):65-76, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, COS Cells, Cadmium Chloride/pharmacology, Cell Nucleus/*metabolism, Cells, Cultured, Cercopithecus aethiops, Humans, Interferon-beta/pharmacology, Mice, Mice, Transgenic, Multiprotein Complexes/drug effects/*metabolism, Mutation, Neoplasm Proteins/drug effects/*metabolism, Nerve Tissue Proteins/genetics/*metabolism, Nuclear Proteins/drug effects/*metabolism, Peptides/genetics, Proteasome Endopeptidase Complex/drug effects/*metabolism, Protein Isoforms/drug effects/metabolism, Transcription Factors/drug effects/*metabolism, Tumor Suppressor Proteins/drug effects/*metabolism.



9. M. Latouche, P. Fragner, E. Martin, K. H. El Hachimi, C. Zander, A. Sittler, M. Ruberg, A. Brice, and G. Stevanin. Polyglutamine and polyalanine expansions in ataxin7 result in different types of aggregation and levels of toxicity. Mol Cell Neurosci, 31(3):438-45, 2006. Note: Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, Brain/*metabolism/pathology/physiopathology, Cell Line, Cells, Cultured, Humans, Intranuclear Inclusion Bodies/genetics/*metabolism/pathology, Molecular Chaperones/genetics/metabolism, Nerve Tissue Proteins/genetics/*metabolism/toxicity, Neurofibrils/genetics/metabolism/pathology, Neurons/*metabolism/pathology, Peptides/*metabolism, Proteasome Endopeptidase Complex/genetics/metabolism, Protein Folding, Rats, Spinocerebellar Ataxias/genetics/metabolism/physiopathology.



10. S. Traver, M. Marien, E. Martin, E. C. Hirsch, and P. P. Michel. The phenotypic differentiation of locus ceruleus noradrenergic neurons mediated by brain-derived neurotrophic factor is enhanced by corticotropin releasing factor through the activation of a cAMP-dependent signaling pathway. Mol Pharmacol, 70(1):30-40, 2006. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Animals, Blotting, Western, Brain-Derived Neurotrophic Factor/*pharmacology, Cell Differentiation/*drug effects, Cells, Cultured, Corticotropin-Releasing Hormone/*pharmacology, Cyclic AMP/*metabolism, Dose-Response Relationship, Drug, Drug Synergism, Enzyme Activation/drug effects, Gene Expression/drug effects, Locus Coeruleus/cytology/drug effects/metabolism, Mitogen-Activated Protein Kinase 1/metabolism, Mitogen-Activated Protein Kinase 3/metabolism, Neurons/cytology/*drug effects/metabolism, Norepinephrine/metabolism, Norepinephrine Plasma Membrane Transport Proteins/genetics/metabolism, Rats, Rats, Wistar, Receptor, trkB/genetics/metabolism, Receptors, Corticotropin-Releasing Hormone/genetics/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction/*drug effects, Tyrosine 3-Monooxygenase/genetics/metabolism.

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