1. P. Rizk, J. Salazar, R. Raisman-Vozari, M. Marien, M. Ruberg, F. Colpaert, and T. Debeir. The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells. Neuropsychopharmacology, 31(6):1146-57, 2006. Note: Comparative StudyJournal ArticleResearch Support, Non-U.S. Gov'tUnited Statesofficial publication of the American College of Neuropsychopharmacology. [WWW] Keyword(s): Animals, Benzopyrans/*pharmacology, Brain-Derived Neurotrophic Factor/metabolism, Bromodeoxyuridine/diagnostic use, Cell Count/methods, Cell Differentiation/*drug effects, Cell Survival/drug effects, Chromatography, High Pressure Liquid/methods, Hippocampus/*cytology, Imidazoles/*pharmacology, Immunohistochemistry/methods, In Situ Nick-End Labeling/methods, Male, Microdialysis/methods, Neural Cell Adhesion Molecule L1/metabolism, Neurons/*drug effects, Norepinephrine/metabolism, Rats, Rats, Sprague-Dawley, Receptors, Adrenergic, alpha-2/*antagonists & inhibitors, Sialic Acids/metabolism, Time Factors.



2. T. Debeir, M. Marien, J. Ferrario, P. Rizk, A. Prigent, F. Colpaert, and R. Raisman-Vozari. In vivo upregulation of endogenous NGF in the rat brain by the alpha2-adrenoreceptor antagonist dexefaroxan: potential role in the protection of the basalocortical cholinergic system during neurodegeneration. Exp Neurol, 190(2):384-95, 2004. Note: Journal ArticleResearch Support, Non-U.S. Gov'tUnited States. [WWW] Keyword(s): Acetylcholine/metabolism, Animals, Benzopyrans/*pharmacology, Brain Ischemia/pathology/physiopathology, Enzyme-Linked Immunosorbent Assay, Imidazoles/*pharmacology, Immunohistochemistry, Nerve Degeneration/*drug therapy, Nerve Growth Factor/*drug effects/metabolism, Neurons/*drug effects/metabolism/pathology, Neuroprotective Agents/*pharmacology, Rats, Receptors, Adrenergic, alpha-2/antagonists & inhibitors, Somatosensory Cortex/blood supply/*drug effects/pathology, Up-Regulation.



3. G. U. Hoglinger, P. Rizk, M. P. Muriel, C. Duyckaerts, W. H. Oertel, I. Caille, and E. C. Hirsch. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci, 7(7):726-35, 2004. Note: Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S.United States. [WWW] Keyword(s): Aged, Analysis of Variance, Animals, Antiparkinson Agents/therapeutic use, Bromodeoxyuridine/metabolism, Case-Control Studies, Cell Count/methods, Cell Death/physiology, Cell Division/drug effects, Cells, Cultured, Dopamine/*deficiency/physiology, Dopamine Antagonists/pharmacology, Dopamine Plasma Membrane Transport Proteins, Drug Interactions, Ependyma/ultrastructure, Female, Glial Fibrillary Acidic Protein/metabolism, Glycoproteins/metabolism, Humans, Immunohistochemistry/methods, In Situ Nick-End Labeling/methods, Indoles/therapeutic use, Intermediate Filament Proteins/metabolism, Levodopa/therapeutic use, Male, Membrane Glycoproteins/metabolism, Membrane Transport Proteins/metabolism, Mice, Mice, Inbred C57BL, Microscopy, Confocal/methods, Microscopy, Immunoelectron/methods, Microspheres, Middle Aged, Nerve Tissue Proteins/metabolism, Neural Cell Adhesion Molecule L1/metabolism, Neurons/metabolism/*pathology/ultrastructure, Olfactory Bulb/cytology/metabolism, Oxidopamine/toxicity, Parkinson Disease/drug therapy/*metabolism/*pathology, Parkinsonian Disorders/metabolism/pathology, Postmortem Changes, Rats, Rats, Sprague-Dawley, Receptor, Epidermal Growth Factor.

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